Searchable abstracts of presentations at key conferences in endocrinology

ea0063gp230 | Adrenal and Neuroendocrine - Clinical (1) | ECE2019

Low-dose pollutant mixture triggers metabolic disturbances in ovariectomized mice and comparison with the effects of 17β-estradiol (E2) treatment

Julien Benoit , Vega Nathalie , Pinteur Claudie , Vidal Hubert , Naville Danielle , Le Magueresse-Battistoni Brigitte

Introduction: Environmental pollutants especially those endowed with endocrine disrupting activities have been shown to contribute to metabolic related diseases suggesting that hormonal deficit conditions as observed in post-menopausal women may constitute aggravating conditions. To explore this hypothesis, we used the model developed in the laboratory which consists in a chronically exposure of mice to low-dosed chemicals in mixture incorporated in a high-fat-high-sucrose die...